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Might Bite will go straight to the King George following his comfortable success in Sandown's Future Stars Intermediate Chase.
The RSA and Midmay hero was shortened from 7-2 to 3-1 following his eight length victory ahead of December Gold Cup winner Frodon.
The eight-year-old, who is well known for almost handing his Festival win to stablemate Whisper, jumped soundly and Nico De Boinville didn't work too hard to finish home unchallenged.
Henderson, who has won the King George twice with Long Run (2010 and 2012), is relishing the Boxing Day showdown.
"It was straightforward. His jumping was great," said the Champion trainer.
"He just needed a run and I think he was running a bit fresh. He settled well and he jumped beautifully. That was ideal.
"Our objective is the King George and most agreed the sensible thing was to come here (rather than the Betfair Chase at Haydock).
"He won't run again until then and he'll be miles straighter than he was today. That's part one done.
"Our job is now to get him there on Boxing Day quite a lot fitter than he was today. I wouldn't say a racecourse gallop would go amiss, actually.
"We'll try and win the King George and then make a second-half-of-the-season plan."
He went from 10-1 to 8-1 for the Cheltenham Gold Cup following the win.